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信号转导与发育机理研究组

作者:佚名    来源:实验中心    发布时间:2018/1/8 15:11:41    点击量:    【打印文章】

团队人员:

1.         研究组长:林鑫华研究员,首批国家千人计划高层次海外引进人才,“973”计划首席科学家。 1984年毕业于杭州大学生物系,获学士学位;1987年毕业于中国科学院上海细胞生物学研究所,并获得硕士学位;1995年毕业于美国华盛顿大学,获得博士学位。1995年至2000年在哈佛大学医学院进行博士后研究。2000-2008年受聘于美国辛辛那提儿童医院发育生物学系,历任助理教授、副教授、教授。2008年受聘于温州医科大学,组建信号转导与发育机理研究组。目前担任中国动物学会理事、中国细胞生物学会北京分会副理事长;任国际期刊 Developmental DynamicsFlyThe Open Cell Signaling Journal  编委,担任《细胞生物学学报》副主编。

2.         工作人员:叶晓蕾、冯颖、林益

研究方向

       从多个重要的信号通路包括Wg、Hh、TGF-β等出发,利用果蝇全基因组RNAi文库、果蝇全基因组过表达文库和蛋白质组学等多种手段,筛选 鉴定参与形态发生素信号通路的新基因,研究这些基因在形态发生素梯度形成和信号转导中的功能和机制,以及对眼发育的影响。


Laboratory of signal transduction and development mechanism

Team members

1.         Principal Investigator: Xinhua Lin, PhD

Xinhua Lin is recruited by the "Thousand Talents Plan" and the chief scientist of "973" plan. He graduated from the Department of Biology, Hangzhou University in 1984 with a bachelor's degree and later got his master’s degree from the Shanghai Institute of Cell Biology, Chinese Academy of Sciences in 1987. Then Dr. Lin received his PhD from Washington University in 1995 and completed a postdoctoral training in Harvard Medical School from 1995 to 2000 .From 2000 to 2008, Dr. Lin worked successively as an Assistant Professor, Associate Professor and Full Professor in Cincinnati Children’s Hospital Medical Center. Dr. Lin became the PI of signal transduction and development mechanism research group in Wenzhou Medical University since 2008. Also, he was appointed as the member of editorial board of journal of Development Dynamics and Fly

2.         Team staff: Xiaolei Ye, Ying Feng, Yi Lin

Scope of Research Proposal

1.       Screening and identifying the new genes involved in Wg, Hh and TGF-β and other morphogen related signal transduction pathway.

      2.     Reveal the mechanism and function of these new genes in eye development.